The hydro-methanolic extract of T. ciliatum improved histopathological changes in the liver by inducing antioxidant defense enzymes superoxide dismutase (SOD); elevating GSH (non-enzymatic antioxidant glutathione); and reducing lipid peroxidation, nitric oxide (NO), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) levels in thioacetamide (TAA)-induced liver failure [129]. This evidence concerns the gene GPT and liver failure.