UCP1 and obesity due to melanocortin 4 receptor deficiency: In this regard, BAT is associated with the expression of genes related to thermogenesis, mainly the uncoupling protein 1 (UCP-1), and it has become a critical point in obesity research due to adaptive thermogenesis, which is the process of heat production regulated in part by the catabolism of substrates without the release of energy by ATP; while WAT has the main function of storing lipids.