Although the dysregulation of VEGF is a hallmark of pathological conditions such as tumor angiogenesis and exudative “wet” AMD, this factor is crucial for normal vasculature physiology and has also been shown to mediate neuroprotection and even neurorescue of dopaminergic neurons in vivo and in vitro models of Parkinson’s Disease [12,15,42]. Here, VEGFA is linked to age-related macular degeneration.