To investigate the function of FZR1 in in breast cancer patients with NACT, Liu S et al. collected 193 specimens from breast cancer patients who underwent NACT, including 14 cases of Luminal A, 122 cases of Luminal B, 45 cases of HER2+, and 12 cases of Basal 12. The gene discussed is FZR1; the disease is breast carcinoma.