Indeed, single-cell RNA-sequencing of cancer cells revealed significant differences in LDHB expression between and within cancer, stroma, and immune subpopulations of primary breast cancer tumors [59] (see also https://www.ebi.ac.uk/gxa/sc/experiments/E-GEOD-75688/results?geneId=ENSG00000111716). The gene discussed is LDHB; the disease is cancer.