To our knowledge, this is the first study to investigate the use of anti-vinculin antibodies in scleroderma patients with ILD considering that our search of PubMed for studies was published in January 2022 using the following query ("Pulmonary Fibrosis"[Mesh]) AND "Scleroderma, Systemic"[Mesh]). The gene discussed is VCL; the disease is scleroderma.