Retinoschisin-deficiency, known to result in XLRS pathology, causes an increasing mislocalization of the retinal Na/K-ATPase and the Kv channel subunits Kv2.1 and Kv8.2 during postnatal retinal development of the XLRS mouse retina. This evidence concerns the gene KCNV2 and X-linked retinoschisis.