CD4 and Alzheimer disease: The results showed that the AD group had significantly higher proportions of naive B cells (p = 0.0210), M1 macrophages (p = 0.0090), neutrophils (p = 0.0497), CD4 naive T cells (p = 0.0101), and gamma delta T cells (p = 0.0070), and lower proportions of plasma cells (p = 0.0056) and follicular helper T cells (p = 0.0314) than the ND group.