SULT2A1 and Alzheimer disease: Despite the growing body of evidence that steroids, in particular cortisol and DHEAS, might be incriminated in the etiopathogenesis of AD and might be considered potential therapeutic targets, there have been very few studies that assessed both cortisol and DHEAS levels in human subjects with MCI or AD type dementia (Maninger et al., 2009; Ouanes and Popp, 2019).