TRPC6 and status epilepticus: In the hippocampus of mice with pilocarpine-induced status epilepticus, a significant increase in protein expressions of TRPC3 and TRPC6 was found in comparison with those in controls (Leuner et al., 2013); using anti-TRPC6 antibody to inhibit TRPC6 expression in status epilepticus, mice cause synaptic reorganization characterized by reduced dendritic arborization and spine density of hippocampal CA3 area (Leuner et al., 2013).