fosB KO mice showed an increased number of hilar ectopic cells after kainic acid (KA)-induced acute seizures (Yutsudo et al., 2013), and manifested increased anxiety (Ohnishi et al., 2011), in agreement with our IL-17A data demonstrating that reduced EGC production in IL-17A KO could attenuate epilepsy-associated anxiety. The gene discussed is FOSB; the disease is epilepsy.