Specifically, mutations in a number of chromatin regulators have been associated with neurodevelopmental disorders such as Rett syndrome (MECP2), intellectual disability (CHD1, CHD2, CHD7, CHD8, ATRX, and KDM5C), epilepsy (CHD1, CHD2, CHD7, CHD8) (Consortium et al., 2013), and ASD (MECP2, CHD1, CHD2, CHD3, CHD7, CHD8, MBD1, MACROD2, H2AFY, ARID1B, SMARCC1, SMARCC2, and JMJD1C) (reviewed in LaSalle, 2013). The gene discussed is CHD8; the disease is Intellectual disability.