A follow-up study of alternative KCC2 transcripts further identified increased expression of transcript EXON6B (with a new exon 6) in SZ patients but the same transcript was reduced in patients with major depressive disorder (MDD), while other alternatively spliced transcripts examined including AK098371 (truncated KCC2 transcript), EXON2B (with a new exon 2), and ΔEXON6 (with exon 6 deletion) were not found to be different (Tao et al., 2012). Here, SLC12A5 is linked to major depressive disorder.