LGALS3 and obesity due to melanocortin 4 receptor deficiency: Gal-3 has been considered in neurodevelopment, neuroinflammation, and neurodegeneration, also regarding its interplay with neurotransmitters (Borovcanin et al., 2021a), as well as its possible modulation by antipsychotic treatment and consequent obesity and cognitive changes in schizophrenia (Borovcanin et al., 2021b).