These newly identified lncRNAs may play an important role in the development of NPC by competing for miR-142-3p, thereby regulating some important mRNAs, such as BIRC5, CDK1, and TOP2A. Based on this finding, we propose further in-depth research using the co-expression networks to yield new discoveries about the mechanisms governing NPC. Here, CDK1 is linked to nasopharyngeal carcinoma.