PREX1 and astrocytoma (excluding glioblastoma): Since LGG had the highest correlation between high PREX1 expression and reduced patient survival, we focused our essentiality analysis on the astrocytoma context, which includes the 42MGBA cell line, to reveal in detail its essentiality profile of genes coding for signaling proteins, aiming to identify potential P-Rex1 partners in LGG oncogenic settings.