PREX1 and central nervous system cancer: Only lower grade glioma (LGG) and acute myeloid leukemia (LAML) showed reduced survival among the group of cancer patients with high PREX1 expression, while kidney renal clear cell carcinoma (KIRC) and lung adenocarcinoma (LUAD) showed the opposite relationship, a better survival for the high PREX1 expression groups (Figure 1A).