The incidences of severe (grade ≥3 according to CTCAE v4.0) leucopenia, neutropenia, febrile neutropenia, anorexia, diarrhea, nausea/vomiting, as well as the increases in creatinine, AST, ALT, hyponatremia, and lung infection were observed during the treatment. The gene discussed is GPT; the disease is Decreased total neutrophil count.