(52) analyzed the significance of NLR in peripheral blood and the immune infiltrate profiles (i.e., number of CD8+ and FOXP3+ tumor infiltrating lymphocytes (TIL) and programmed cell death ligand 1 (PD-L1) expressions) in the pretreatment biopsies to establish their potential relationship with the response to iCHT. This evidence concerns the gene CD274 and neoplasm.