In order to gain insight into a potential role of GR in the cellular radiation response we treated the cancer cells with the documented GR inhibitor 2-acetylamino-3-[4-(2-acetylamino-2- carboxyethylsulfanylthio-carbonylamino)-phenylthiocarbamoylsulfanyl]propionic acid (AAPA) (47, 48) (Figure 5A). This evidence concerns the gene GSR and cancer.