showed that two peripheral blood parameters, lymphocyte count and C-reactive protein level, had the highest correlation with recurrence compared to other parameters, and low preoperative LCR was significantly associated with undifferentiated histology, advanced T-stage, lymph node metastasis, distant metastasis, and advanced grade; reduced preoperative LCR was an independent prognostic factor for disease-free and overall survival, and was an independent risk factor for postoperative complications and surgical site infections in colorectal cancer patients; Wenting Ou (25) et al. Here, CRP is linked to metastatic malignant neoplasm in the lymph nodes.