In addition to being a regulator of cellular DNA repair (60), USP1 is also involved in the occurrence and development of various human diseases, such as USP1, plays a key role in the Fanconi anemia pathway (60), is a potential target for differentiation therapy (66), is upregulated in breast cancer, and is associated with poor patient prognosis (67). The gene discussed is USP1; the disease is breast carcinoma.