By using IHC staining of 10 human colorectal adenocarcinoma specimens, we confirmed that hnRNPA1, hnRNPA2B1, hnRNPC, hnRNPK, hnRNPR, and hnRNPU were mainly localized in the nucleus and had higher expressions in colorectal adenocarcinoma tissues compared with adjacent normal tissues (ANT) (Figures 2A, B). This evidence concerns the gene HNRNPA1 and colorectal adenocarcinoma.