Given the central role of the liver in the production of albumin, acute-phase reactants, and coagulation factors, liver dysfunction may affect multisystem manifestations of COVID-19, such as acute respiratory distress syndrome (ARDS), coagulation disorders, and multiorgan failure 6, 8, 24, 95-97, thereby exacerbating symptoms of COVID-19. This evidence concerns the gene ALB and acute respiratory distress syndrome.