In fact, expression levels of intercalated cell marker genes in BHD-associated kidney cancers exceeded their expression level in normal kidney, thereby supporting that the acquisition of intercalated cell characteristics in BHD-associated kidney cancer may be because of upregulation of FOXI1 and its driven genes (Figures 4H and S3A–S3D and Dataset S3). The gene discussed is FOXI1; the disease is kidney cancer.