METTL3 and oral cavity squamous cell carcinoma: Moreover, our preliminary study found that methyltransferase-like protein 3 (METTL3) increased the stability of c-Myc by establishing m6A modification on the 3′ untranslated regions (3′UTRs; near the stop codon) of c-Myc to influence oral squamous cell carcinoma (OSCC) cell invasion, migration, and proliferation, which revealed the relationship with the negative prognosis and tumorigenesis of OSCC patients (14).