Moreover, our preliminary study found that methyltransferase-like protein 3 (METTL3) increased the stability of c-Myc by establishing m6A modification on the 3′ untranslated regions (3′UTRs; near the stop codon) of c-Myc to influence oral squamous cell carcinoma (OSCC) cell invasion, migration, and proliferation, which revealed the relationship with the negative prognosis and tumorigenesis of OSCC patients (14). Here, MYC is linked to oral cavity squamous cell carcinoma.