MTOR and epilepsy: To date, a range of molecular pathways have been implicated in epilepsy, from the Janus kinase (JAK)/Signal transducer and activator of transcription (STAT) pathways to tropomyosin receptor kinase B (TrkB) and its neurotrophin brain derived neurotrophic factor (BDNF), REV-Erb alpha (Rev-Erbα), mammalian target of rapamycin (mTOR), among others (Kim et al., 1997, 2021; Tanaka et al., 1997; Brandon et al., 2000; Terunuma et al., 2008; Vaz et al., 2008; Weston et al., 2014; Zhang et al., 2021).