USP10 and chronic myelogenous leukemia, BCR-ABL1 positive: SKP2 acts as co-regulator of K63-linked ubiquitination of Bcr-Abl for its activation. While USP10 deubiquitinates and stabilizes SKP protein levels and amplifies Bcr-Abl activation in chronic myeloid leukemia cells (Liao et al., 2019)