LRRK2 and Parkinson disease: Moreover, biomarkers for the activity of autophagy could also provide information concerning the autophagy-related endosomal, lysosomal and secretary pathways; synucleinopathy processes, axonal damage biomarkers and even inherited PD-related mutations (DJ-1, LRRK2) (Youn et al.; Pan et al., 2008; Xicoy et al., 2019a).