ELMO1 and type 1 diabetes mellitus: Studies analyzing the role of ELMO1 in kidney function described an aggravation of nephropathy in mice with type 1 diabetes (Shimazaki et al., 2005; Hathaway et al., 2016) and a promotion of glomerular injury through dysregulation of the extracellular matrix (ECM) (Shimazaki et al., 2006) in presence of ELMO1.