Moreover, the expression of AP3S1 was found to be significantly reduced in Esophageal carcinoma (ESCA), Glioblastoma multiforme (GBM), Kidney Chromophobe (KICH), Acute Myeloid Leukemia (LAML), Lower Grade Glioma (LGG), Ovarian serous cystadenocarcinoma (OV), Skin Cutaneous Melanoma (SKCM), Testicular Germ Cell Tumor (TGCT), Uterine Corpus Endometrial Carcinoma (UCEC) (Figure 1A and Supplementary Table S1). Here, AP3S1 is linked to acute myeloid leukemia.