The core members of this subfamily include p120-catenin, Arvcf (Armadillo gene deleted in velocardiofacial syndrome), δ-catenin, and p0071, all of which, except for p0071, have been detected in mature lens tissue (Straub et al., 2003; Jun et al., 2012; Maddala and Rao, 2017). Here, ARVCF is linked to 22q11.2 deletion syndrome.