AKT1 and cancer: GSEA results revealed that the DEGs were mainly enriched in the pathways including cytokine-cytokine receptor interaction, chemokine signaling pathway, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, transcriptional misregulation in caner, proteoglycans in cancer, phagosome, NOD-like receptor signaling pathway, natural killer mediated cytotoxicity, focal adhesion, and cell adhesion molecules (Figure 4B; Supplementary Table S5).