We found that the low-risk ELncSig group was more positively related to tumor-infiltrating immune cells, such as CD8+ T cells, macrophages, Th2 cells, and major histocompatibility complex (MHC) class I. Subsequent immune-related scores also showed that the low-risk ELncSig group had a better immune microenvironment. The gene discussed is HLA-C; the disease is neoplasm.