In addition, studies have shown that LINC00184 (the competing endogenous RNA (ceRNA))directly binds to miR-145 and inhibits its expression, to promote the expression of Ang2 and induce the epithelial-mesenchymal transition (EMT) characteristics of gastric cancer cells, and improve the carcinogenesis mediated by Ang2 (41). This evidence concerns the gene ANGPT2 and gastric cancer.