The second phase, which is much more crucial in COVID-19 because it is an intracellular viral infection, results in the secretion of a variety of cytokines into the bloodstream by T cells and macrophages, of which IL1-β, IL-2, IL-8, IL-10, IL-6, IL-12, IFN-γ, and TNF-α are the best known (4, 5). This evidence concerns the gene TNF and COVID-19.