Consistent with our findings in Nkg7+/+ and Nkg7-/- littermates, Nkg7 sgRNA-electroporated OT-I T cells (sgNkg7) demonstrated significantly reduced killing of MC38-OVA tumor cells compared to OT-I T cells electroporated with a non-targeting control guide (sgNT) (Figure 6D). The gene discussed is NKG7; the disease is neoplasm.