TREM2 and metabolic dysfunction-associated steatohepatitis: From these observations and the notion that NAMs are involved in forming crown-like structures in NASH livers (21), we went to investigate whether SB3 might influence the expression of NAM markers such as TREM2 and CD9 along with that of the fibrogenic Galectin-3 (Gal-3) (38–41) which is specifically associated with the macrophage phenotype (18–21).