SHH and medulloblastoma: Still, recurrent mutations of DDX3X have been reported in medulloblastoma (a common childhood hindbrain tumor), mainly in wingless-type MMTV integration site family (WNT)-activated medulloblastomas and sonic hedgehog (SHH)-activated medulloblastomas (Jones et al., 2012; Northcott et al., 2012; Pugh et al., 2012; Robinson et al., 2012; Patmore et al., 2020).