CD14 and obstructive sleep apnea syndrome: A recent study investigated the effect of OSA on different subtypes of monocytes (classical monocytes: CD14++CD16−, intermediate monocytes: CD14+CD16+, non-classical monocytes: CD14dim+CD16+) in patients with untreated OSA, who have an average AHI of 17.8 ± 16.96/h (21).