Effect of clinical stage, surgical margins, adjuvant treatment (tumor lysate vaccine alone or plus MC), inflammatory indices (NRL, PLR, MLR, SII, and CRP/ALB ratio), albumin, LDH, and frequency of circulating cells (lymphocytes CD4, CD8, CD4/CD8 ratio, Tregs, (M)-MDSCs, and (PMN)-MDSCs) on the PFS and OS of 25 canine patients with oral melanoma. The gene discussed is CRP; the disease is neoplasm.