Several oncogenes and tumor suppressor genes, including Myc, epidermal growth factor (EGF), phosphoinositol three kinase (PI3K), mTOR, and hypoxia-inducible factor 1α (HIF-1α), are involved in the metabolic switch from oxidative phosphorylation (OXPHOS) toward altered glycolysis of tumor cells (Dang, 2012; Lu et al., 2015). The gene discussed is EGF; the disease is neoplasm.