Mechanistically, Patiño-Morales et al. demonstrated that the cytotoxic effect of curcumin against cervical cancer cells involved promotion of the complex it forms with NAD(P)H quinone dehydrogenase 1 (NQO1), leading to its stabilization, thus avoiding the interaction between p53 and its negative regulator ubiquitin ligase E6-associated protein (Patiño-Morales et al., 2020) (Figure 3). The gene discussed is NQO1; the disease is cervical carcinoma.