The links with glycobiology (Pucci et al., 2021), Ca2+ homeostasis (Jones and Hazlehurst, 2021) and the cytoskeleton (Leggett et al., 2021) were also explored, while the complexity of its interrelationships with CSCs (Roy et al., 2021), p53 (Parfenyev et al., 2021) or H2O2 signaling (Milton and Konrad, 2022), and their consequences on the generation of circulating tumor cells (CTCs) (Topa et al., 2022) or occurrence of a collective invasion process (Nagai et al., 2020) were updated. Here, TP53 is linked to neoplasm.