In a CKD mouse model established by adenine gavage, Ophiocordyceps lanpingensis polysaccharides elevated SOD and GSH-PX, decreased ROS and MDA, improved histopathological staining, and decreased fibrosis-related proteins TGF-β1, α-SMA, and collagen I (Zhou et al., 2021). Here, SOD1 is linked to chronic kidney disease.