Molecular analysis of the contents of cystic neoplasms has also been carried out, and mutations in KRAS, GNAS, and RNF43 have been found to serve as markers of mucinous neoplasms, especially GNAS mutations that serve as diagnostic markers of IPMNs.30, 31, 32, 33, 34, 35, 36. This evidence concerns the gene GNAS and cystic neoplasm.