Herein, our study is consistent with previous studies and results show that BTN3A2 expression was remarkably positively linked to invading levels of tumor purity, B cells, neutrophils, CD8+ T cells, macrophages, and dendritic cells, and CD4+ T cells, B cells, and dendritic cells were linked with a good prognosis of LUAD. Here, BTN3A2 is linked to neoplasm.