In this work, we established and validated a novel prognostic signature of PAAD that utilized 10 PRlncRNAs, including TRAF3IP2-AS1, LINC00519, LINC01133, LINC02251, AC005332.6, AL590787.1, AC090114.2, TRPC7-AS1, MIR223HG, and MIR3142HG. Here, MIR223HG is linked to pancreatic adenocarcinoma.