Furthermore, in comparison of three different human renal carcinoma cell lines and their corresponding sunitinib-resistant cell lines, the risk scores of the sunitinib-resistant 786-O cell line were significantly higher than those of the parental cell line, while this trend was not observed in the other two cell lines (Caki-1 and A498).Through verification in ccRCC cell lines and their respective sunitinib-resistant cell lines, it was found that CPT1B played a more important role in the drug-resistance mechanism of ccRCC. Here, CPT1B is linked to renal carcinoma.