Eissa et al. (2014). found that the expression of DLGAP5 (HURP) RNA in urine sampler could be detected, which might be a biomarker of bilharzial and nonbilharzial bladder cancer. It is reported that DLGAP5 may be a potential prognosis factor in lung cancer, breast cancer, pancreatic cancer, endometrial cancer, and colorectal cancer (Shi et al., 2017; Branchi et al., 2019; Ke et al., 2020; Xu et al., 2020; Zhang et al., 2020). This evidence concerns the gene DLGAP5 and lung cancer.