TOP2A and cutaneous melanoma: As shown in Figure 3B, TOP2A mRNA expression was significantly upregulated in tumors than in the normal control tissues, including adrenocortical carcinoma (ACC), lymphoid neoplasm diffuses large B-cell lymphoma (DLBC), brain lower-grade glioma (LGG), ovarian serous cystadenocarcinoma (OV), pancreatic adenocarcinoma (PAAD), sarcoma (SARC), skin cutaneous melanoma (SKCM), thymoma (THYM), uterine carcinosarcoma (UCS).