Our results based on the TCGA database showed that TOP2A mRNA was amplified in 31 out of 33 available tumor tissues except for testicular germ cell tumors, which only showed an increased trend without statistical significance in the tumor than in the normal control tissues (Our results based on TCGA database showed that TOP2A mRNA was amplified in 31 out of 33 available tumor tissues except for testicular germ cell tumors). This evidence concerns the gene TOP2A and neoplasm.