As shown in Figure 3B, TOP2A mRNA expression was significantly upregulated in tumors than in the normal control tissues, including adrenocortical carcinoma (ACC), lymphoid neoplasm diffuses large B-cell lymphoma (DLBC), brain lower-grade glioma (LGG), ovarian serous cystadenocarcinoma (OV), pancreatic adenocarcinoma (PAAD), sarcoma (SARC), skin cutaneous melanoma (SKCM), thymoma (THYM), uterine carcinosarcoma (UCS). This evidence concerns the gene TOP2A and adrenal cortex carcinoma.