Galectin-8 has been found to be involved in tumour development and metastasis, in part due to its stimulatory effect on angiogenesis and lymphangiogenesis.17 This function also makes galectin-8 an important player in graft rejection, where it interacts with endothelial growth factors.18 Galectin-8 also has a broader function in inflammation for the immune response,19 and is involved in the neuroprotective environment in the brain.20 This evidence concerns the gene LGALS8 and neoplasm.