KCNA3 and Arrhythmia: This study seems to suggest that the conclusion that antipsychotics cause arrhythmias by inhibiting potassium channel currents or prolonging the QT interval is validated by the need for multifaceted support, that concentration dependence is not established as an indicator of arrhythmia ipso facto, and that effects of the PI3K pathway can also produce arrhythmias (70–72).