Lastly, in a study of 24 men and women at risk for T2D, consumption of HAMS resulted in a significantly lower fasting, 2-h, and 3-h insulin incremental areas under the curve during an oral glucose tolerance test, while fasting insulin resistance measures using the homeostasis model assessment of insulin resistance were significantly lower (Dainty et al., 2016). This evidence concerns the gene INS and type 2 diabetes mellitus.